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Grishok, A. et al. Genes and mechanisms related to RNA interference regulate expression of the small temporal RNAs that control C. elegans developmental timing.
Cyclic strain evokes the expression of the small leucine-rich proteoglycans decorin and biglycan in 2D cultures and native tissues.
Goal of this study was to analyze the expression of the small and large isoforms of TN-C in non-small cell lung cancer (NSCLC) and determine its functional significance.
This study corroborates preceding transcriptional profiling results showing that Foxf, an early component of the cardiopharyngeal GRN, previously shown to impact protrusive activity by regulating the expression of the small GTPase Rhod/f16, also connects the GRN to cellular effectors capable of sensing and responding to the extracellular milieu.
Retinal neuron loss in Grn-KO mice is preceded by nuclear depletion of TDP-43 and accompanied by reduced expression of the small GTPase Ran, which is a master regulator of nuclear import required for nuclear localization of TDP-43.
Expression of the small heat shock protein (hsp) genes can be induced in cultured Drosophila cells by high temperature shock and by exposure to physiological doses of the insect molting hormone ecdysterone.
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There was also increased expression of the smaller group of oncogenes and other genes which are associated with typical diseases of old age.
We also examined the expression of the small-heterodimer partner (SHP), which can heterodimerise with activated receptors and prevent transactivation of DNA as it lacks a DNA binding domain [27].
However, expression of the smaller utrophin isoforms is not abolished in the uko strain used by Rafael et al [4].
Subsequently, Shah et al [4] demonstrated preferential inactivation of the longer CAG repeat alleles resulting in expression of the smaller alleles that predictably increase the androgen sensitivity.
The fadD1 promoter immediately downstream of this regulatory element was induced by LCFA (e.g. C18 1Δ9), and initiated the expression of the smaller fadD1 transcript (Fig. 2C, 3A and 3B).
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