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Another study by our group revealed a different mechanism of PTTG1 suppression by T3/TRs, showing that T3 stimulation in TR-expressing hepatoma cells inhibited expression of specificity protein 1 (Sp1), thereby suppressing PTTG1, a direct transcriptional target of Sp1.
"To detach this expression of specificity, by changing the identifications of three white firemen, is to move away from what makes it powerful," said Mr. Burns.
Importantly, miR-22 upregulation decreased the expression of specificity protein 1 (SP1) and estrogen receptor 1 (ESR1) and vice versa, suggesting that they are targets of miR-22 [ 78].
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To assess the impact of using β-actin as a reference gene, we examined relative expression of dual specificity phosphatase-10 (Dusp10) without and with normalization to either 18S, the geometric mean of three stable reference genes (α-tub, TfR, GAPDH) or β-actin following TNFα exposure.
In order to exclude the pairs whose apparent coexpression pairs are simply due to their narrow tissue-specific expression patterns, we searched for Gene Atlas in Genevestigator [ 21] for the expression of condition specificity.
The objective of this study was to analyze the expression of dual-specificity phosphatase 9 (DUSP-9) and determine its clinical significance in human ccRCCs.
The expression of dual-specificity tyrosine- Y -phosphorylation regulatyrosine- Y -phosphorylationll-styrosine- Y -phosphorylations and mouse models, has been found to be inconsistent acregulatedous expression profiling studies involving the brain of Ts1Cje mice.
Expression specificity of modules is expressed as the percentage of module members specifically expressed in a particular tissue/condition (and across all arrays) with an expression specificity index above 1.
In 2011, a simulation study by Martinez-Veracoechea and Frenkel discussed how ligand valency, binding strength, and level of receptor expression affect specificity of binding.
Here we found that mutant WT1 inhibits the expression of the dual specificity phosphatase genes DUSP3 and DUSP16.
Here we show that this line harbors a transgene insertion that disrupts expression of the dual specificity phosphatase 27 (dusp27) gene.
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