Sentence examples for expression of specific genomic from inspiring English sources

Thus, the strong associations between retrotransposon expression and the placenta might represent expression of specific types of retrotransposon, or even expression of specific genomic copies of a retrotransposon, rather than a widespread general activation of retrotransposon expression in this tissue.

Since both copy number and epigenetic alterations result in changes in gene expression patterns, analysis of microarray gene expression data in the context of specific genomic regions is an efficient means of integrating the effects of genomic changes in cancer.

This process involves RNA-directed DNA methylation and systemic silencing of specific genomic locations.

Therefore, to investigate if the overexpression of lamin B1 affects gene expression in specific genomic regions, we performed a positional gene set analysis using GSEA (21).

Seamless fosmid recombineering was used to generate reporter gene fusions with minimal modification to assay expression of specific transcripts while maintaining the broad genomic DNA context and alternative transcript production.

It will be important now to determine if this is a direct genomic effect or if expression of specific HIV gene products is involved.

Genomic imprinting, which results in the parental-specific expression of specific genes, plays an important role in normal growth and development [ 1].

The genomic effects of GCs are generally mediated by cytosolic receptors that alter the expression of specific genes [ 12].

New post genomic biotechnologies such as transcriptome analyses are efficient in characterising the pool of genes involved in the expression of specific biological functions.

We decided to rely on the 'Flp-in T-REx' (HEK293) system (Life Technologies) to achieve a tightly controlled expression of exogenous FXN as it allows generation of stable mammalian cell lines using Flp-recombinase-mediated integration of an expression cassette at a specific genomic location.

The transcriptional transactivation function of the isolated E2 variants and the specific genomic expression profiles was also examined.