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For statistical analysis of survival curve, we classified the pAKT expression of score 0 or 1+ as pAKT negative, score 2+ or 3+ as pAKT positive.
As Table 2 shows, we first compared the crude expression of score values for MMPs and TIMPs between PINs, HBPs and prostate carcinomas.
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Among the 51 patients with high LAT1 expression (score of 3 or 4), 39 (76.5%) displayed high expression of CD98 (score of 3 or 4) and 12 displayed low expression (6 patients with a score of 2 and 6 patients with a score of 1).
We employed the same Quick score system to quantify ER expression, although not statistically significant, a trend toward positive correlation between high expression of ER (score of ≧12) and ENO1 overexpression was found (P = 0.063, Table 3).
Sixty-nine NSCLCs which had an expression of AQP5 (score = 2 or 3) were reassembled in two TMA blocks for FISH analysis, each.
A strong expression of CD73 (score 2+) was found in 46 of 174 patients (26.4%), whereas in 48 patients (27.6%) a weak immunoreactivity (score 1+) was detected.
Expression of Snail (score 1+, 2+, and 3+) was detected in 37.5% of primary ovarian cancers and in 52% of corresponding metastases (Table 2B).
High expression of EGFR (score above 200) did not correlate with positivity of AKT, ERK1/2, or STAT3 (P > 0.5 for all proteins).
The staining was reviewed and expression of TPL2 scored for intensity and proportion by Dr. Jonathan Melamed at NYU.
Expression of antibodies scored separately in amniotic epithelium, Wharton's jelly, endothelium, and smooth muscle cells of artery and vein.
The expression of ERα was scored by assigning a proportion score and an intensity score according to Allred's procedure [ 12].
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