The importance of this heterologous gene expression for safety considerations was further supported by analysing fusions between the aforementioned promoters and a promoter-less cytotoxin gene.
Selective AAVP homing, tumor-associated vascular expression of TNFα, systemic safety, and RECIST-based objective responses were observed (same species therapeutic index).
Unlike the issues of journalism and freedom of expression, journalists' safety has not been a popular topic of academic research.
Two promoters (P CMV and P PH) were shown to be able to direct expression of a bacterial cytotoxin, which illustrated the relevance of this type of heterologous gene expression for the specification of safety measures for the handling of genetically modified organisms.
Whatever the motivation for the carnage, prime minister Jens Stoltenberg understood the threat that such an attack poses to the fabric of Norwegian society, aimed at the values Norwegians cherish most – their openness, freedom of expression and their feeling of safety.
The term "safety climate" generally refers to the outward expression or measurable components of "safety culture" such as management behaviors, safety systems, and employee perceptions of safety [ 5].
Limit equilibrium has been used, and expressions for the factor of safety against sliding and overturning mode of failure have been proposed.
This paper presents closed-form expressions for the factor of safety and yield coefficient of slopes subjected simultaneously to seismic forces and variable groundwater conditions.
As someone who grew up black and Caribbean on a council estate in Luton, much of what Hanley writes rings true: the yearning for respect as an expression of self-worth; the safety of a group identity; the sense of being under attack and the consequent desire to stick it to the Man.
Cell-based gene delivery for gene therapy offers the advantages of long-term stable expression of proteins without the safety concerns associated with viral vectors.
