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It has been described that testosterone regulates the expression of multitude of genes in the lacrimal/meibomian glands in the ovariectomized mice model [ 13].
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The epigenetic system is a self-organizing regulatory level of organization that operates above the genome and provides the high level of flexibility needed for coordinated and context-dependent expression of multitudes of genes.
Adhesion and followed invasion of N. gonorrhoeae to host cells is known to alter expression of a multitude of proteins in host cells.
Lymphocyte development consists of an irreversible progression of cells through distinct developmental stages which is regulated by the coordinated expression of a multitude of transcription factors [1], [2], [19].
MYC encodes a transcription factor that regulates the expression of a multitude of genes involved in regulating cellular proliferation and growth and when overexpressed results in the prototypical pathologic features of cancer as described above [3], [4].
Furthermore, IL-28A stimulation resulted in an at least two-fold decreased expression of a multitude of genes (272 genes for p<0.01 without multiple testing adjustment; 89 genes for adj.-p<0.05) with up to 9.3-fold reduced levels (Table 4).
RGs were analyzed for the expression of a multitude of neural and progenitor markers by comparative qPCR.
Recent analyses suggest they affect the expression of a multitude of genes, beyond the homeotics whose alteration in expression lead to their initial discovery.
NF- κB pathway regulates the expression of a multitude of genes involved in the immune system, growth, inflammation, and cancer development [ 1– 3].
It can bind a variety of bile acids [ 32, 33] and subsequently regulate the expression of a multitude proteins that transport bile acids across cell membranes [ 34- 36].
These results indicate that the PPAR γ agonists differentially regulate the expression of a multitude of stemness and differentiation factors in BTSCs.
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