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In this setting, the immune reaction against the adenoviral vector eliminates the delivered gene within 10 days (Dai et al, 1995), causing transient VEGF expression of insufficient duration to allow stabilization and persistence of newly induced vessels, similar to a clinical scenario with immunologically normal patients.
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However, the expression of Fab59 was insufficient to support in vivo characterization of the Fab due to extremely low expression levels from its initial phage display expression vector.
Thus expression of antigens was insufficient to induce T cell activation after co-culture of transfected cells and peripheral blood mononuclear cells (data not shown).
Emphasis is now made on the exclusive expression of D2S as "insufficient" or "not permissive" for cocaine-induced plasticity in D2 receptor-GIRK signaling.
It is probable that the decreased expression of PTHrP is insufficient to inhibit abnormal hypertrophy in repair tissue; therefore, supplement of exogenous PTHrP to diseased cartilage is of great significance.
For example, the integrin associated protein focal adhesion kinase (FAK) is a critical determinant of cell migration, yet similar to the small GTPases of the Rho family, the expression of FAK is insufficient to transform primary cells [ 42, 48].
However, these studies overlooked the problem that the spinosyn biosynthetic pathway was unbalanced: the expression of six genes in the spinosyn biosynthetic pathway was insufficient; Saccharopolyspora spinosa accumulated useless compounds because of insufficient expression of SpnK.
Figure 2a shows that the lethal growth phenotype of icd can be partially recovered by expressing MA4265, while the expression of this gene was insufficient to rescue the growth of the leuB and yeaU mutants.
While it is likely that the U6atac mutant phenotype results from the combined influence of insufficient expression of several U12-type intron-containing genes and their downstream effects, our data suggests that disruption of the prohibitin complex functions may play a central role.
Those with an average Ct value greater than 30 were discarded because of insufficient expression.
Therefore, it is possible that we failed to observe a broad protective effect of 14-3-3 14-3-3 14-3-3insufficient expression.
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