Sentence examples for expression of hallmark from inspiring English sources

Gene expression of hallmark genes by RNA sequencing and qPCR.

Changes in the expression of hallmark N- or P-acquisition genes were not observed upon addition of nitrogen or phosphorus to nutrient depleted cultures.

Over expression of hallmark of HNSCC such as CCND1, MYC, MET, CTNNB1, JAK1, HRAS, JAG1, and HES1 and down regulation of FBXW7, SMAD4 in at least 3 cell line were observed and validated by quantitative real time PCR (Additional file 2: Table S3).

Expressions of hallmark proteins and transcription of GADD45α mRNA were determined by Western-blot and RT-qPCR methods, respectively.

Expression of several hallmark plasma cell differentiation and survival genes were confirmed using quantitative real-time PCR.

In fact, the short discussion about cancer hallmarks is an excellent introduction that points out the way in which analysis of gene expression can lead to the understanding of changes in expression of particular ("hallmark") pathways.

Loss of E-cadherin, overexpression of N-cadherin, and cytoskeletal alterations (e.g., expression of vimentin) hallmark this process causing phenotypical and structural changes that lead to acquisition of motility and invasiveness of cells that have undergone EMT.

In this regard, commitment to the Treg cell lineage is exemplified by expression of the hallmark transcription factor FOXP3 and occurs in either the thymus or the periphery (Josefowicz et al., 2012).

A total of 20 in 32 ROS oxidative marker genes were up-regulated, including high expression of four hallmarks, and preferentially expressed genes associated with ROS-scavenging including thioredoxin, glutaredoxin, and alternative oxidase genes.

As expected, we were able to demonstrate that treatment of PMDC05 cells with the TLR4 agonist LPS or the TLR7 agonist gardiquimod led to increased release of lactate, increased glucose consumption, enhanced accumulation of itaconate, as well as increased expression of HIF1α the hallmarks of metabolic reprograming in innate immune cells (Fig. 4a c).

The authors determined that the induction of HSP25/27 expression levels and the change in the pattern of expression were hallmarks of the response of the allograft to CAN-related hypoxia and oxidative stress.