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We investigated whether the ubiquitous transcription factor Sp1 is abnormally expressed in schizophrenia, and consequently can affect the expression of genes implicated in this disorder.
Gene-expression analysis revealed that these cells share a transcriptional profile that includes expression of genes implicated in silencing the virus.
Roschke, A. V. et al. Chromosomal instability is associated with higher expression of genes implicated in epithelial-mesenchymal transition, cancer invasiveness, and metastasis and with lower expression of genes involved in cell cycle checkpoints, DNA repair, and chromatin maintenance.
To identify potential targets of Nsf-mediated fusion, we examined the expression of genes implicated in stabilizing synapses and found that transcripts for multiple genes including brain-derived neurotrophic factor (bdnf) were significantly reduced in nsf mutants.
PPARs also control the expression of genes implicated in the inflammatory response via negative interference with different inflammatory pathways, such as NFκB, AP-1, C/EBP β, STAT-1 and NFAT.
We found that podocytes express 2 NFAT family members and that Gq-dependent activation of these NFAT isoforms induces expression of genes implicated in the progression of kidney disease such as cyclooxygenase 2 (COX2).
Expression of genes implicated in strategy II, the nicotianamine aminotransferase, OsNAAT1 (Os02g0306401) (Inoue et al. 2008), and a receptor like protein RMC, OsRMC (Os04g0659300), recently shown to be involved in regulation of iron acquisition in rice (Yang et al. 2013), were up-regulated under iron excess.
These have enabled evaluation of the consequences of prostate-specific expression of genes implicated in human prostate cancer.
To further explore these differences we examine the temporal gene expression of genes implicated in biofilm development and stress adaptations.
Large, dynamic changes in expression of genes implicated in metabolism, general adaptive responses, membrane structure, and virulence have been reported [8], [9], [10].
cAMP also regulates gene transcription through cAMP-response element binding protein (CREB), a transcription factor that regulates expression of genes implicated in neuroplasticity and cognition [4], [5].
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Justyna Jupowicz-Kozak
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