Sentence examples for expression of genes classically from inspiring English sources

We noted no significant difference in the expression of genes classically associated with drug resistance between chemosensitive and chemoresistant tumours.

Despite the up-regulation in neutrophil activation-related genes, we did not observe changes in the mRNA expression of genes associated with classically or alternatively activated macrophages.

This induced phenotype is characterised by the coordinated expression of pro-inflammatory genes classically associated with immune-mediated cancer rejection (Wang et al, 2008; Galon et al, 2013).

Strikingly, patients with high pretreatment expression of genes defined in the myeloid phenotype and M1 classically activated monocytes, but not high levels of lymphoid subset or B-cell genes, showed a greater 16-week good EULAR response to infliximab treatment.

(a) Expression of genes encoding histone chaperones.

Though existing gene chips can also be used to track the expression of genes, they require knowing in advance the DNA sequence of the genes to be monitored.

The products of the sirtuin genes work by regulating the expression of genes and modifying the activity of enzymes.

This results from alterations in the expression of genes and not through changes in the genes themselves.

mRNA levels of Agrp, Pomc and Npy, ARC-expressed genes classically associated with the control of food intake, were not affected by the manipulation of Fto expression.

Using real-time quantitative RT-PCR we determined that the ARC-expressed genes classically associated with the control of food intake, namely, Agrp, NPY and Pomc were not affected by altered Fto expression (Fig 5).

The expression of classically oestrogen-dependent genes that are downregulated in almost all AI-treated tumours17 supported a significant phenotypic impact of ESR1 mutations providing further evidence for the likely benefit from some therapeutic interventions.