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It was not possible to analyse patients who crossed over between modalities because there is no single equivalent expression of dose clinically validated for both CRRT and IRRT.
We therefore chose to express the dose of CRRT and IRRT based on current clinical practice rather than a theoretical equivalent expression of dose [see Additional data file 1].
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In other words, selection for male-specific function has masculinized the allelic composition of the genome or the level of gene expression of dose-dependent genes.
The "3 + 3 design" is used in many cancer peptide vaccine clinical studies; however, it is reportedly difficult to identify the MTD if the expression of dose-dependent toxicity is not observed.
Gene expression profiles of dose response were used in a supervised analysis using binary regression methodologies as described previously [27].
This finding inspired the suggestion of a combined expression of insulin dose and A1C, formulated as a specific definition of the IDAA1C = A1C (percent) + 4 × [insulin dose (units per kilogram per 24 h)].
E2 stimulated expression of PCNA dose dependently, and GEN also stimulated expression of this proliferation marker.
These results suggest that persistent expression of BMP4 dose not cause formation of solid bone.
Both water-soluble and-insoluble UFP fractions up-regulated the expression of F3 dose dependently, especially at 24 hr post-exposures.
Adenoviral-mediated expression of BAF60a dose-dependently stimulates the transcription of genes involved in peroxisomal and mitochondrial fatty acid β-oxidation.
The expression of lethal doses of MEKK1 resulted in a strong activation of all three major MAP kinase families JNK, ERK, and p38.
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