Sentence examples for expression of deficient from inspiring English sources
We wondered whether this was also the case for cholesterol accumulation triggered by the expression of deficient NPC1 protein.
The abscission zones of bp flowers are notably enlarged, similar to those of flowers with constitutive expression of INFLORESCENCE DEFICIENT IN ABSCISSION (IDA) [ 26].
Moreover, we have shown that suppression of either wild-type β6 expression or expression of β6 deficient in the binding domain for ERK2 dramatically inhibits colon cancer cell growth (Ahmed et al, 2002).
Telomere defects are unlikely to be responsible for the differentiation block of Smg6-deficient ESCs because ectopic expression of NMD-deficient Smg6 (∆14-3-3-Smg6 and ∆PIN-Smg6) in Smg6∆/∆ ESCs could rescue the telomere, but not the differentiation, defects (Fig 4).
As expected, expression of transport-deficient variants was toxic to these cells.
Expression of kinase-deficient RSK2 had no effect on Tat expression as confirmed by western blot analysis (Figure 1C).
Zhao et al. led a study indicating that suppressing STAT3 expression of Smad4-deficient pancreatic cancer cells could prevent TGFbeta-induced invasion by short hairpin RNA [ 117].
Ectopic expression of GJIC-deficient chimeric Cx26 was sufficient to induce EMT and gefitinib insensitivity in HCC827 and PC9 cells, while knockdown of Cx26 reversed EMT and gefitinib resistance in their GR cells both in vitro and in vivo.
This finding is in accordance with earlier studies showing that replication-competent adenoviruses may supply viral replication and repackaging proteins in trans to facilitate the spread and expression of replication-deficient adenoviruses [ 24].
Over-expression of phosphorylation deficient mutants of FOXO proteins (FOXO1-TM, FOXO3A-TM and FOXO4-TM) induced FOXO transcriptional activity, which was further enhanced by resveratrol.
Stewart et al. studied the transmission of mtDNA mutations introduced into the mtDNA mutator mice due to the expression of a proofreading deficient mtDNA polymerase [49].
