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While current smoking is accurately identified based on blood mRNA levels, smoking cessation for more than one year is accompanied by a "normalization" of the expression of certain mRNAs, making it difficult to distinguish former smokers from never-smokers.
Another way is that the expression of certain mRNAs may directly lead to new protein synthesis.
In addition, given the RNA nature of lncRNAs and miRNAs, it is intriguing to speculate that lncRNAs and miRNAs can coordinately regulate the expression of certain mRNAs.
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Several studies indicate that piRNAs in Drosophila have the capacity to downregulate the expression of certain mRNA targets via a miRNA-like mechanism that operates by imperfect base-pairing rules.
Opioids modify the expression profile of certain mRNAs in many tissues, including central nervous system (CNS), the main target of drugs of abuse [ 5].
This mutation apparently contributes to differences in the expression of certain spliced mRNAs encoding NOD1 protein isoforms lacking repeats within the LRR domain.
The idea of specific translational control during pollen development also gains credence from the identification of pollen specific translation factors [8] [10] and preferential expression of certain translation factor mRNAs [11].
We found that the use of cRNA probes was crucial to examine mRNA expression of certain TGFb responsive genes.
There is evidence of positive correlations between mRNA expression of certain lipogenic genes/transcription regulators and intramuscular fat content in crossbred cattle [ 11].
To investigate the underlying mechanism, we evaluated the effect of PCEE on the mRNA expression of certain proinflammatory cytokines related inflammation and proliferation.
However, changes in the mRNA expression of certain proteins were not associated with changes in the protein expression (i.e. L-FABP and INSIG2).
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