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BRM is not a regulator of this pathway, because the expression of autonomous pathway components is not affected in brm.
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If man's autocracy, his genius, his powers of generation, have all passed to the machine, and if the pulpy, material base for the refined and abstract thoughts and emotions that we read in books has been revealed to us, then how can we understand poetry or prose as the sublime self-expression of autonomous and elevated individuals?
By distinguishing between the problem-oriented minimisation of unsustainability and a possibility of vision-oriented sustainability, it can be more clearly articulated how expressions of autonomous, intrinsic or self-determined motivation are the driving forces of a sustainability characterised by individual and planetary flourishing in contrast to a sustainability characterised by survival.
Christianity was a necessary but now transcended stage in the development of the human spirit, to be supplanted by new expressions of autonomous self-consciousness.
It is assumed that these differences arise from a loss of afferent input in preparations that are accessible to intracellular recording, resulting in expression of purely autonomous spike activity.
The fundamental difference between the two is disagreement on whether consent to 'unknown' future activities, can be labelled 'informed consent' and be viewed as an expression of an autonomous will.
It thus appears that EBV possesses intrinsic and extrinsic modes for reactivation from latency, namely expression of and autonomous signaling by LMP2A as well as extracellular B cell stimulation through surface receptors such as the BCR.
One possibility to explain the effect of BRM mutations on FLC is that BRM activates the expression of an autonomous-pathway component.
DOI: http://dx.doi.org/10.7554/eLife.12223.003 10.7554/eLiFigure23.004 Figure 1 figure supplement 1. Relating ectopic EGFR-mCitrine expression with endogenous EGFR expression levels and dependency of autonomous EGFR activation on EGFR expression levels.
Hence, the areas of proper child development and socialisation, the promotion of autonomous expression, identity, problem solving skills, more security, and independence are all being left behind.
However, strong constitutive expression of the cell-autonomous resistance GTPase, Irga6 (IIGP1), was found in mouse liver, contrasting with previous evidence that expression of this protein is exclusively dependent on induction by IFNγ.
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