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Monocyte- and DC-specific enhancers were gradually established at progenitor stages before the expression of associated genes.
To study the roles of leptin on tube formation (as a measure of cellular angiogenesis) and expression of associated genes in first-trimester human extravillous trophoblast cells.
A new analytical expression of associated gain is derived using linear noisy two-port theory, and used to explain a previous experimental observation of lower (worse) associated gain in SiGe HBTs featuring lower (better) noise.
In order to investigate the influence of CGI methylation on the expression of associated genes, their mRNA levels were investigated via qRT-PCR.
In order to determine the impact of CGI methylation on the expression of associated genes, we detected mRNA levels of a subset of genes via qRT-PCR.
Hence, the different profiles of 24-nt sRNAs may influence the expression of associated genes to regulate the phenotypes.
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These findings suggest that hypo-methylation of certain CGIs that typically become hyper-methylated during carcinogenesis might be a common event in breast and ovarian carcinoma cell lines with acquired doxorubicin resistance, but does not lead to re-expression of associated genes.
Evidence was based mainly on statistical association of chromatin marks with expression levels of associated genes.
To capture the full picture presented by the data, the analysis of expression levels of associated genes is indispensable.
This physiological state of inflammation was also associated with enhanced expression of genes associated with cell proliferation.
One might suspect that the observation is due to high expression of genes associated with broad promoters, and low expression of those associated with peak promoters.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com