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Ectopic expression of active PKD2 induced transcriptional activation of Mef2D and inhibited transcriptional activity of Pax3 in these cells.
Therefore, western blotting alone is not adequate for exploring the relationship between activity and expression of active complexes.
Our results showed that cPLA2 activation induced the expression of active caspase-3 and PARP-1.
We next evaluated the temporal expression of active caspase-3 during CD8+ T cell activation in vivo.
Similarly, expression of active Notch was found to downregulate AR activity in prostate cancer cells.
To date, however, expression of active recombinant S6K has not been feasible as S6K activation requires a cascade of phosphorylation events.
We describe expression of active recombinant plant mismatch endonucleases and modification of their activities.
Given the precedents that link Erk5 activation to cell proliferation [10], it is possible that expression of active Erk5 may contribute tumour proliferation.
Immunohistochemical analysis showed cytoplasmic expression of active caspase 9 with moderate staining intensity.
orf3 and orf4 were not necessary for the expression of active enzyme in E. coli.
Regardless of their mechanism, these alterations yield the same molecular end result the expression of active, nuclear-localized YAP/TAZ.
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