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PhoPQ was shown to influence the expression of a vast set of virulence-associated genes in Salmonella [16].
The expression of a vast majority of pro-inflammatory genes, induced in early TB lesions, was repressed in late TB lesions, relative to normal lung.
Pro- and anti-inflammatory stimuli alter the expression of a vast array of transcription factors and chromatin remodelers.
Overexpression of PGC-1α induces the expression of a vast amount of genes participating in mitochondrial metabolism including the TFs ERRA and NRF2 [ 14, 26].
However, the expression of a vast majority of newly identified v-ErbA target genes is either repressed by T3 or does not vary in response to T3 and RA.
In particular, IL-6 and tumour necrosis factor-α are the key pro-atherogenic cytokines, which induce the expression of a vast array of inflammatory responses of endothelial cells and macrophages, whereas vascular endothelial growth factor enhances atherosclerotic plaque formation.
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The local signalling as a consequence to these inflammatory molecules results in the expression of an vast array of protease and consequent degradation of extracellular matrix (ECM) of the articular cartilage and the adjacent bone [ 1, 2].
Less emphasis was given to the sample at 49 hours, since the expression profiles of a vast number of genes were apparently influenced by the major physiological impact of D-glucose addition two hours earlier, which was not the focus of this study.
Because of PRLR expression in a vast majority of tumour specimens and its negative impact on overall survival, the receptor represents a novel prognosticator and a promising drug target for patients with SCCHNs.
So far, more than 800,000 samples have been analyzed, covering the gene expression in a vast array of organisms and disease states.
The ocean is a vast expression of a spirituality that calms my mind while exercising my physical boundaries and leaves me in awe.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com