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Caloric restriction normalizes expression of a substantial percentage of these genes.
Exposure to a pathogen or vaccination introduces changes in the expression of a substantial fraction of these genes.
These data show that PT alters the expression of a substantial number of genes that results in a decrease in pro-inflammatory and cell recruitment responses.
Since this effect was inferred from DNAm profiles, it would appear that the expression of a substantial number of genes characterising bood cell types is under direct epigenetic regulation.
Thus, local diminished expression of a substantial subset of 22q11 genes could alter hindbrain morphogenesis, differentiation and patterning.
We recently found that the expression of a substantial number of genes governing glucose metabolism was greatly altered during Xenopus tadpole tail regeneration 3.
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Based on the expression of EpCAM, a substantial number of HCC cases consist of progenitor cells and their heterogeneous progeny with a capacity to self-renew and limitlessly divide [ 60, 91, 94].
Our high-throughput sequencing data showed that the expression levels of a substantial number of miRNAs were altered in at least one of the three cell lines after TDP-43 knockdown.
Our results indicate that CNAs in myeloma impact the gene expression level of a substantial number of genes.
Treatment of C2 cells with masitinib resulted to a significant change in mRNA expression levels of a substantial number of genes.
These results suggest that chromosome copy number changes in myeloma could have direct effect on the expression level of a substantial number of genes.
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