Hence it is appropriate to express each principal component by the average expression of a (small) group of proteins in order to benefit from the intrinsic noise suppression of averaging as well.
Importantly, they are not as strongly influenced by differential expression of a small number of highly expressed genes [ 17].
Tagami, K. et al. Expression of a small (p ppGpp synthetase, YwaC, in the (p ppGpp 0 mutant of Bacillus subtilistriggers YvyD-dependent dimerization of ribosome.
The discovery of methods to convert somatic cells into induced pluripotent stem cells (iPSCs) through expression of a small combination of transcription factors has raised the possibility of producing custom-tailored cells for the study and treatment of numerous diseases.
Rehli, M. et al. Transcription factor Tfec contributes to the IL-4-inducible expression of a small group of genes in mouse macrophages including the granulocyte colony-stimulating factor receptor.
Two objectives require to be fulfilled: regional activation and permanent maintenance of expression of a small set of driver regulatory genes; and control of large sets of effector genes by these drivers.
Using the chromosome conformation capture technique we have analyzed the expression of a small 2.5-kb gene, CD68, in different human cell types and show for the first time that short-range interactions may also be critical.
When direct overlap in binding to DNA does occur, it occurs through an ERRE embedded within an ERE11, and when in place, this functional relationship can be used to fine tune the expression of a small subset of specific genes11,12,13,14.
The results revealed that significant differences in the expression of a small subset of proteins were observed between exponential and stationary growth phases at both low and high glycerol concentrations.
The analysis generated a set of regression models that, when weighted and combined according to posterior probabilities implied by the statistical analysis, identify patterns in expression of a small subset of genes that are associated with survival and have value in assessing survival risks.
This technique is a relatively inexpensive technology for assaying the expression of a small number of genes.
