Sentence examples for expression of a plethora from inspiring English sources

Nuclear factor kappa B (NF-κB) is a major pro-inflammatory transcription factor controlling the expression of a plethora of genes involved in inflammation and immune responses [60].

The fact that in vivo inhibition of PARP-1 reduced the expression of a plethora of chemokines could partially explain the absence of inflammatory infiltrates in the joint tissues of AIQ-treated mice, being especially relevant for chemokines as MIP-2 (chemotactic for neutrophils) and Rantes (for macrophages and T cells), all involved in CIA pathogenesis [21], [22].

miRNAs modulate both physiological and pathological pathways by post-transcriptionally inhibiting the expression of a plethora of target genes.

The transcription factor NFκB is a crucial regulator of immune and inflammatory responses, controlling the expression of a plethora of genes including cytokine, cytokine receptor, chemokine, cell adhesion molecule, and other cell surface receptor genes [ 42, 43].

Phosphorylation of myocyte-specific enhancer factor 2 (MEF2) and CCAAT-enhancer binding protein (C/EBP β [ 354] has also been reported, thereby triggering the expression of a plethora of genes involved in cell type-specific differentiation.

We now add data that methylation of CpG dinucleotides also may play a key role in controlling expression of a plethora of genes involved in directing tissue specificity and diverse organ function.

Alterations in the expression levels of a plethora of miRNAs will add another level of regulatory control over these responses.

Non-coding RNAs (ncRNAs) are sequence-specific regulators of gene expression, mediating a plethora of cellular responses to changing environmental conditions and morphological differentiation.

For the analysis of expression profiling data a plethora of methods has been developed in order to rank genes by t-statistics [ 22- 24].

Beyond the well-established Escherichia coli, mammalian cell culture and baculovirus-infected insect cell expression systems, a plethora of alternative expression systems has been discovered, engineered, matured and deployed, resulting in crystal, nuclear magnetic resonance, and electron microscopy structures.

For gene expression studies, a plethora of computational methods have been developed in order to identify genes that are differentially expressed in different conditions, thereby linking gene expression to changes in cellular status.