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Expression of a minimal set of 17 predicted miR-34b/34c/449 target genes derived from the developmental process GO category was identified from a training set to classify 41 AD and 17 SCC, and correctly predicted in average 87% of 354 AD and 82% of 282 SCC specimens from total 9 independent published datasets.
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Four of these series included expression data of a minimal number of 50 NSCLC patients treated by surgery with linked information on survival, GSE11969 [ 18], GSE13213 [ 19], GSE14814 [ 20], and GSE19188 [ 21].
In ER+, PR+, and HER2+ cell lines, because of low expression, a minimal amount of AnxA2 is present at the cell surface.
The control of Tag expression by a minimal CEA gene promoter allows the tumor-directed expression of CEA by crossing CEA424/SV40 Tag-transgenic mice with human CEA-transgenic C57BL/6 mice, which express the CEA transgene in a similar spatiotemporal expression pattern as found in humans[ 13, 14].
Expression of a panel of minimal response elements as well as the c-fos promoter failed to provide a response to brevetoxin, indicating that the HEK cells lack a necessary intermediate signaling component.
A mixed media work on paper by Robert Kaupelis called "Better Bite Site" (2002) is frenzied, forceful and a bit whimsical while Christopher Magadini's two teeny paintings "Bio" (2002) and "Squared" (2003) achieve a formidable sense of spatial relations and visceral expression within a minimal amount of space.
However, EBV clonality postinfection may be a consequence of the selective growth advantage achieved by optimal LMP2A expression over a minimal number of TRs [28].
It is also found that, without sacrificing much fidelity in terms of the resulting spectrum, the model function can be antisymmetric leading to a compact analytical expression with a minimal number of parameters.
First, we selected IORs with RNA-seq expression exceeding a minimal value of read counts based on the previously annotated sRNAs as well as annotated ORFs (protein coding mRNAs).
A human wild-type BRAF cDNA was cloned into a pBKS plasmid with its expression under the control of a minimal promoter containing multimerized tet-operons.
The expression of LTβR (as a minimal characteristic of FDC precursors), and of DRC-1 and CD21L (FDC-specific markers) was studied with both immunocytochemical staining (LTβR and DRC-1) and RT-PCR (CD21L).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com