Sentence examples for expression of a direct from inspiring English sources
Whether skin involvement represents the expression of a direct autoimmune attack, or an unrelated event still remains to be defined.
To confirm that absolute Yan-YFP concentration had little effect on cell state transitions, we examined expression of a direct target of Yan in R7 cells: the pros gene (Kauffmann et al., 1996; Xu et al., 2000).
Therefore, the use of a prodrug activating enzyme not only is a further safeguard to the system (compared to expression of a direct cytotoxic protein which might produce host toxicity if it comes in circulation), but also provides considerable potential for treatment amplification.
Activated STAT3 signaling also has been shown to induce expression of survivin expression, a direct downstream target of STAT3 and confer resistance to apoptosis in human breast cancer cells [ 7].
We also elucidated the underlying mechanism that p53 restained the osteogenesis via modulating the trancription of pri-miR-17 and then affecting the expression of Smurf1, a direct target of miR-17.
When comparisons across different sites are made, hepatic expression of CYP1A2, a direct target of the AHR, appears elevated in embryos from a site associated with a dioxin point source and previously characterized PCB contamination.
For example, we showed recently that Tip60 up-regulated expression of Col2a1, a direct target of SOX9 [31].
Moreover, expression of ADRB2, a direct target of EZH2 [ 27], was concurrently increased by 50%.
The apoptotic phenotype in SpRunt-1 deficient embryos is specifically caused by a deficit in the expression of SpPKC1, a direct regulatory target of SpRunt-1 that encodes a conventional protein kinase C [ 8].
We found that injection of the Phos-A peptide, but not the A-mut peptide, in Xenopus embryos induced partial axis duplication and the expression of Xnr3, a direct downstream target gene for β-catenin signaling [49] (Figure 6).
As a control, the mRNA expression levels of a direct TGF β target gene, Smad7, were also examined and, as expected, were not affected by CHX treatment.
