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In eukaryotic cells, small non-coding RNAs have been demonstrated to play fundamental roles in gene expression modification during development (Zamore & Haley, [2005]).
ABA synthesis is stimulated by drought and salt stresses and ABA participates in both physiological behaviors such as stomatal movement and photosynthetic regulation (quick processes) and gene expression modification (slow processes) in response to the stresses in plants.
The iCREATE process required ~ 1 month to perform 13 rounds of combinatorial genome modifications with targeted gene knockouts, expression modification by ribosomal binding site (RBS) engineering, and genome-level site-saturation mutagenesis.
Identification of receptors or transporters for dsRNAs in E. histolytica would provide a new example of selective RNA uptake by cells, allowing direct and targeted gene expression modification by exogenous genetic material, as it was initially shown in Caenorhabditis elegans [27].
The present study aims to explore gene expression modification, mainly focused on candidate genes that may regulate the vascular effects of estrogens, in cultured human endothelial cells exposed to physiological concentrations of estradiol by using microarrays, thus providing new information to the available body of knowledge about the influence of estradiol on the vascular wall.
Cognitive processes require gene expression modification, and preclinical studies indicate that ER-activating therapy improves cognition.
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Recent studies have shown that besides changes in transcriptome expression modifications in non-coding RNA species and changes in epigenetic events may also be involved.
We selected eight molecules which induced gene expression modifications which anti-correlated with the infection signature.
We attempted to analyze gene expression modifications according to the chromosome localization.
This is the first study to compare the cellular gene expression modifications induced by five different influenza A virus subtypes.
These gene expression modifications, if translated into altered protein quantities, could increase the potential for RhoA activation.
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