Through cell-by-cell analysis, we showed that a mixture model best represents the small cell population, which comprises cells with low-surface expression, mid-surface expression, and high-surface expression.
These 3 groups displayed different levels of REST target gene expression and could thus be divided into REST enhanced malignancies (REM), tumors with near-normal expression of REST targets (Near-normal), and tumors with mid-range REST target gene expression (Mid-range).
DFP-1 was highly expressed in all the tissues with a more prominent expression in mid gut whereas DFP-4 was exclusively expressed in fat body.
Using light and electron microscope immunocytochemistry on acrylic sections this study shows a similar pattern of expression from mid to late pregnancy in all four ruminants examined [cow, deer, ewe and goat].
Group II: higher expression at mid seed development or later.
We show that Kcnq1 transitions from monoallelic to biallelic expression during mid gestation in the developing heart.
Instead, various growth factors act via ERK to up-regulate cyclin D expression in mid G1 [ 35].
These cells clearly correspond to the Ci-Syn positive ones observed in tail and complete the pattern of Ci-Syn expression in mid tailbud embryos.
There are 84 ChIP seq peaks next to genes that were shown in our previous RNA-seq study [ 26] to undergo changes in expression during mid and late cyst development periods.
The third set, which is only identified using the subtracted library at day 130, contains transcripts with high expression in mid-late lactation including the major WAP, known to be specifically expressed between day 130 and 240 of lactation [ 34], polymeric immunoglobulin receptor, cystatin C and transferrin.
These data indicate a tendency for in vivo effects of propionate to alter hepatic gene expression in mid-lactation cows and neonatal calves, which are consistent with a feed-forward effect of propionate to regulate its own metabolism toward gluconeogenesis through changes in hepatic PCK1 mRNA.
