Androgen receptor expression, a maker of cellular androgen bio activity was similar between wild-type mice and weight stable Apc Min/+ mice and Apc Min/+ mice initiating body weight loss (Fig. 1B).
Since all the cells isolated from the cardiac biopsy were included in HDS in their relative proportion, we had the possibility to study the protein and gene expression of makers for several kinds of cells and the changes with time and culture condition.
In in vitro study BMSC-sheet had a more feasible characteristic upon bone repairing including richer ECM, larger mineralized area and stronger ALP activity in addition with a significant higher mRNA expression of osteogenic maker such as BMP-2, b-FGF, Col 1a1, OSX and Runx-2 than the control group.
The expression of neuronal maker beta III-tubulin was analyzed by immunofluorescence staining as previously described [30].
The two LmnaE82K transgenic mice lines exhibited chamber dilation, increased heart weights, increased fibrosis, upregulation of hypertrophic maker expression, nuclear structure defects and conduction defects (Figures 1, 2, 3, Tables 1, 2), which was similar with the phenotypes of the patients carrying the LMNA E82K mutation.
NMFs and CAFs can be distinguished on the basis of their differential maker expression.
(D ) The frequency of trx mutant type II neuroblasts displaying a type I neuroblast maker expression profile (PntP1−Ase+).
In addition, cancer stem cells typically represent a small number of the total tumor cells which can be enriched on the basis of cell surface maker expression.
Depletion of DKC1 or XPC upregulated the expression of neuroectodermal maker Fgf5 and trophoblast-specifier Cdx2 at the expense of Gata6, a primitive endoderm marker, while mesodermal marker T remained unchanged.
In this condition, we did not observe significant reduction of fibrosis maker expression in the presence of free IFNγ or PPB-PEG-IFNγ, although clear trends were observed for collagen I (Fig. 5D) and collagen III (Fig. 5E).
