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Cyclin D1 and p21Cip1 were found to be downregulated and upregulated, respectively, only in sFRP1-expressing tumors, which might be one reason why the impact of sFRP1 expression is stronger in vivo.
Comparatively, the expression is stronger in asthmatic epithelium and subepithelial layer 24.
Detailed analysis suggests that the expression is stronger in the row of three outer hair cells compared with the inner hair cell (Fig. 1K, inset).
In late third instar larvae and early pupae MIP expression is stronger and follows the same pattern as CCAP (Fig. 1B-C; supplementary material Fig. S1C-D).
Follistatin expression is stronger at the distal-most region of the optic vesicle, both dorsal and ventral, which corresponds to prospective dorsal (see Veien et al., Development, 2008).
Further analysis of our clinical data showed that INH α expression is stronger in benign epithelium and stroma but not the G3/G4 regions of the prostate in patients with lymph node metastasis compared to those with organ-confined disease.
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By 51 hpf, tbx1 expression can be seen in the cardiac outflow tract, the ventricle and the atrium, although by 72 hpf cardiac expression is strongest in the cardiac outflow tract.
During regenerative outgrowth, lef1 expression is strongest in epidermal cells adjacent to newly aligned scleroblasts that secrete bone matrix, while it is low or undetectable in epidermis adjacent to mesenchymal areas with either mature bone or proliferative distal blastema cells.
In gcm mutants, a few glial cells remain, usually those in which gcm2 expression is strongest.
Expression is strongest in the four anterior-most segments of this domain.
In stage 9 larvae, expression is strongest in T2 and the most posterior segments and growth zone.
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