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New knowledge on pathogenesis is being gained from both in vivo and in vitro molecular studies especially where genes are modified and gene expression is manipulated.
When a complex algebraic expression is manipulated, valid manipulations maintain algebraic sub-expressions or act on them in systematic ways; invalid manipulations violate or ignore sub-expressions (Fig. 1c).
More studies in which Bim expression is manipulated are necessary to support such a conclusion.
This is true whether Bim expression is manipulated by the CDK inhibitor (RCV), Bim-directed shRNAi, or by protein synthesis inhibitor (CHX).
In conclusion, an excellent correlation is observed between Bim expression and apoptosis in cAMP-stimulated IPC cells, whether the Bim expression is manipulated by RCV, CHX or various Bim-directed shRNAi hairpins.
2) The central hypothesis of the paper (Yan fluctuations are functionally relevant) can be rigorously tested only if the noisiness of Yan expression is manipulated independently from EGF signaling, e.g. by manipulating transcriptional of translational control elements of Yan.
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The most intriguing abstractionist here, because she depends on quiet expression, is Alma Thomas.
(The expression was Fuller's before it was Dickinson's; the poet is said to have loved Fuller's work).
Jane was, and is, a very shy person: one of her favourite expressions is, "Photographers should neither be seen nor heard".
Does Emily Browning have more than one expression, and is Scott Glenn ready to star in The Iggy Pop Story?
Its most influential published expression is General David Petraeus's 2006 manual "Counterinsurgency".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com