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Furthermore, gene expression is maintained during long-term human iPSC culture and in vitro differentiation along multiple lineages.
Further supporting this idea, PARP14 levels are elevated in early stages, and high PARP14 expression is maintained in late stages of HCC.
"Dark Content" is another complex meditation, on an untenable paradox: the friendliness of the Internet, which seems to invite free expression, is maintained by the hard work of censorship.
Remarkably, PARP14 is overexpressed in early stages of HCC and, importantly, its high expression is maintained during cancer progression, indicating that PARP14 upregulation might be required for both the formation and maintenance of HCC (Supplementary Fig. 1a).
EGFRvIII expression is lost in standard cell culture but its expression is maintained in tumor sphere culture, and cultured cells also retain the EGFRvIII+/CD133+ co-expression and self-renewal and tumor initiating abilities.
In particular, OsCOL4 expression is maintained at a high level in the early vegetative stages but decreases when Ehd1 expression begins (Lee et al. [2010]).
Expression is maintained after fertilisation and during cleavage (not shown).
Supporting the notion that AspM expression is maintained by highly hierarchical progenitors of the brain.
Expression is maintained at reduced levels in the vascular domain and fades in the ground tissue.
Its expression is maintained in the heart throughout prenatal and postnatal life.
This intensity of expression is maintained up to 6 h of culture but thereafter drops markedly.
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CEO of Professional Science Editing for Scientists @ prosciediting.com