In another model (model 2), which, in addition to the above parameters, the HIF1 α and LDH5 were included, the LDH5 expression was emerged as an independent prognostic marker.
Although traditionally linked to the physiology of tissues in 'motion', the ability of the cells to transduce external forces into coordinated gene expression programs is emerging as an integral component of the fundamental structural organization of multicellular organisms with consequences for cell differentiation even from the beginning of embryonic development.
In addition to regulating EBV expression, there is emerging evidence that the microenvironment can also modulate the function of individual virus proteins.
Genome-wide gene expression analysis is emerging as an important tool to study changes in the host immune response to infectious agents, including Mtb [ 54, 55].
Gene expression profiling is emerging as a tool for classifying breast cancers, guiding therapy, and predicting treatment responses (Cheang et al, 2008; Haas et al, 2011).
In addition to clinical and histological characteristics, expression profiling is emerging as a viable means of molecularly subtyping breast cancer, and a recent report has correlated distinct regions of loss of heterozygosity with specific expression profiles [ 34].
A substantial portion of post-transcriptional gene regulation is controlled by microRNA (miRNA) networks, hence an alteration in the expression of miRNAs is emerging as a significant contributing factor to human neurodegenerative disease [10], [11].
Despite this complexity, we find that a consistent picture of gene expression in AD is emerging.
Although there is no consensus, the clinicopathologic importance of ER-β expression in BC is emerging, including its connection with factors usually associated with a better clinical outcome [ 11, 17, 32, 33].
