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(a d) DCN expression in glomerulus of uninjected kidney.
Level of collagen IV expression in glomerulus of (i l) uninjected kidney and (m p) injected kidney.
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Expression of Axl and Gas6 are increased in glomerulus of diabetic rats and HG stimulation of mesangial cells, followed by induction and activation of Gas6/Axl and the Akt/mTOR pathway, which leads to mesangial and glomerular hypertrophy [ 15].
PCNA protein level in glomerulus of (q t) uninjected kidney and (u x) injected kidney.
Because of the expected overlap in the patterns of gene expression in the glomerulus gene set with the normal cortex, we focused our analysis on the cortex gene set.
For validation of the dataset an arbitrary list of known genes with specific or pronounced expression in the renal glomerulus of different species was generated and compared with REGGED (Supplementary Table S2).
In the present study, we first demonstrated that podocytes, epithelial cells in the crescent, and parietal epithelial cells were the major sites of ANXA1 expression in the glomerulus, as well as certain actively regenerating renal tubules.
We observed the low expression of endogenous ALR in the tubulointerstitium and no ALR expression in the glomerulus in the sham-operated kidney tissue by immunofluorescence staining.
Ang II expression was elevated in glomerulus, tubular cells, interstitial cells, and blood vessels (arrows) in group II (b).
Expression of Gas6/TAM was increased in the glomerulus of diabetic rats, which led to mesangial and glomerular hypertrophy [ 15].
Expression of Gas6/TAM was increased in the glomerulus of diabetic rats, which led to mesangial and glomerular hypertrophy (10).
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