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The technique of cyclic voltammetry, and hence the Randles Sevick expression, in conjunction with platinum microelectrodes have been employed to determine the √DCTC value.
Under hypertonic stress Sko1p is phosphorylated by Hog1p and converted into a transcription activator by recruiting SAGA histone deacetylase and SWI/SNF complex to promote chromatin remodeling [25] and induce ENA1 expression in conjunction with Calcineurin/Crz1p mediated pathway [28].
We also use microRNA data from the NCI-60 cell lines to develop microRNA gene expression profiles of chemosensitivity, in an attempt to understand the biologic interplay between relevant microRNA expression in conjunction with the corresponding messenger RNA data, which could potentially refine the predictive ability of gene signatures.
This moderate frequency of expression, in conjunction with the previously demonstrated spontaneous immuogenicity of these five antigens in cancer patients [19], [20], [21], [22], suggest this group of CT antigens as potential cancer vaccines targets for ER-negative breast cancer, including the triple-negative subgroup.
Although a previous report had shown an increase in TG2 protein expression in the small intestines of MTX-dosed rats [42], we were unable to observe significant changes in TG2 expression in conjunction with dose- or time-dependent damage to the small intestinal mucosa of mice treated with MTX (Figures S3, S4).
High levels of Nrf2 expression in conjunction with temozolomide treatment induce cell autophagy in glioblastomas [ 17].
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Therefore, the application of gene expression analyses in conjunction with miRNA expression may have a significant impact for the discovery of new predictive developmental toxicity pathways and biomarkers.
In this same line, a decreased level of BECLIN 1 expression, especially in conjunction with increased expression of BCL-xL, was correlated with poor prognosis in ovarian cancer bearing patients [ 17].
These findings suggest that, when utilized in an integrated approach, microRNA expression profiles in conjunction with corresponding gene expression data may provide a critical link for understanding mechanisms involved in chemosensitivity and chemoresistance.
IL-1β induces Saa3 expression; SAA3, in conjunction with SAA1/SAA2, the expressions of which were also elevated in our RA animal models, induce the transcription of matrix metalloproteinases (MMPs) [ 27].
Finally, using miRNA expression data in conjunction with gene and pseudogene expression levels, they identified 38 pseudogenes with potential to function as ceRNAs in kidney cancer.
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