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Whether EOMES can activate mesodermal gene expression in collaboration with BMP4-SMAD1 signalling remains an unresolved issue.
Furthermore, TGFβ signalling can affect p21Cip1/Waf1 expression in collaboration with FOXO proteins (reviewed in [ 48]), and TGFβ has been reported to be activated by CTDSP2 [ 13].
Phosphorylated IRF-3 forms a dimer, translocates into the nuclei, binds to DNA and regulates the expression of IFNβ expression in collaboration with AP-1 and NF-κB.
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She designed the look in collaboration with Rachel Zoe.
Hepatitis C virus (HCV one of the leading causes of hepatocellular carcinoma strongly triggers AID expression in hepatocytes in collaboration with proinflammatory cytokines [ 53], and ectopic AID expression is observed in human liver specimens with chronic hepatic inflammation caused by HCV infection [ 58].
However, regulation of mRNA stability can facilitate rapid changes in gene expression both independently and in collaboration with transcriptional effects [3] [5].
Pin1 regulates expression of cyclin D1 in collaboration with Ras and Wnt/β-catenin signaling pathways.
They bind to the specific regions, known as cis-elements, in the promoters of genes and then activate or repress the expression of regulated genes in collaboration with other regulatory factors.
A basic 4-plex melon oligo-based gene expression microarray was designed in collaboration with Roche NimbleGen, based on a previously validated probe set derived from 33,000 melon expressed sequence tags (ESTs) from 12 normalized cDNA libraries, which were obtained from different melon tissues from plants grown under different physiological conditions [ 47].
Sample preparation and processing, hybridization to the Human Genome U133 Set, and normalization were performed as described in the Affymetrix GeneChip Expression Analysis Manual (Affymetrix, Santa Clara, CA) in collaboration with Gene Logic Inc (Gaithersburg, MD).
The majority of the work described was carried by JCRC and the cell expression studies were carried out in collaboration with ECJMV and GE.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com