Taken together, our results support the hypothesis that neuronal cells are less sensitive to progerin expression, regardless of its sustained expression in adulthood.
Mgmt was found in clusters (clusters 11 and 23, male and female, respectively) which exhibit a trend toward of increasing expression in late adulthood (between 21 weeks and 104 weeks) which is consistent with previous reports associating Mgmt with aging phenotype [ 40].
This inchoate tendency appears to foreshadow the full expression of authoritarianism in adulthood -- both the lack of openness to new ideas and the strict reliance on automatic, mindless judgments and decision making.
The neural and epithelial expression of CCM1 in adulthood suggests that cavernous malformations may be the result of primary neural defects.
Lower expression levels of α2-AR in the iWAT of CR male animals persisted in adulthood, while expression of β3-AR was not different from controls.
In adulthood, the expression of snx3 mRNA is observed in the cerebral cortex, hippocampus, piriform cortex, and cerebellar neurons.
On the other hand, these findings are in agreement with the fact that we could not detect Cdc42 expression in supporting cells of control mice at adulthood, neither in normal conditions nor in response to ototoxic challenge, as analyzed by in situ hybridization at days 2 and 7 post-lesion (data not shown).
In the Adult ADHD Self-Report Scale (ASRS) [ 51], 18 items corresponding to the 18 ADHD symptom criteria of DSM-IV are worded to be more reflective of the expression of ADHD symptoms in adulthood.
Impaired habituation in rpm-1 mutants was not rescued by expression of RPM-1 in adulthood, which suggests that habituation defects are a developmental consequence of rpm-1 dysfunction.
The lower expression levels of α2-AR persisted in adulthood in CR animals, while expression of β3-AR was not different than controls at the age of 6 m.
