Sentence examples for expression in a substantial from inspiring English sources

Interestingly, TCGA data indicated little or no RIP3 expression in a substantial fraction of colon cancers compared with normal tissues (N=304) (Supplementary Figure S6).

The involvement of MYB in epithelial tumors was first suggested by the amplification of MYB in certain colon carcinoma-derived cell lines [ 10], and by its expression in a substantial proportion of tumors [ 7, 11].

Interestingly, 37% of the oligos had a 2-fold change or more in expression, indicating a substantial difference in genetic background of these groups of tumors.

It is likely that the lower expression of FAD3A reduces accumulation of linolenic acid levels in N0304-303-3, but the residual FAD3A expression in N0304-303-3 combined withethe FAD3B and FAD3C expression still result in a substantial amount of linolenic acid in seeds.

Even after 76 hr, Rex1GFPd2 expression was maintained in a substantial subset of cells (10%20%%) (data not shown).

By evaluating ALCAM reactivity in tumor cells we were able to show that ALCAM expression is present in a substantial portion of tumors but does not correlate with prognostic markers like clinical stage, grading, age or histological type, or with patients' survival.

Abrogation of MYC expression by siRNA resulted in a substantial increased expression of estrogen-stimulated miR-26a and miR-26b, indicating that c-MYC was a mediator of estrogenic repression of miR-26a/b expression.

Exposure to a pathogen or vaccination introduces changes in the expression of a substantial fraction of these genes.

As shown in Figure 1D, expression of RAP2.1 resulted in a substantial reduction of the expression of the reporter gene FLUC.

As expected, Western blot analysis of Cav-1 expression showed a substantial increase in Cav-1 protein level in the Cav-1-transfected cells, whereas a significant decrease in Cav-1 level was observed in the shRNA-Cav-1-transfected cells as compared with the control-transfected cells).

Concomitant with a significant decrease in LacCer expression a substantial reduction of GM2 and a complete lack of GM3 expression can be assigned to the highly metastatic sublines of L1-cells.