To investigate the involvement of Sema3A in RA pathogenesis, we performed immunohistochemical staining for Sema3A, VEGF165 and NRP1 expression in serial synovial serial sections from RA and OA patients.
In addition, a knockdown of SOX2 led to significant inhibition of HNSCC CSC stemness-associated features, such as self-renewal capacity, stem cell expression markers, chemoresistance (through ABCG2 expression), and tumorigenesis, in a serial-dilution xenograft.
On average, 1 to 3 differentially displayed bands were selected per reaction, based on the following criteria: 1) differential expression between B2 (arthritic) versus F6 (normal); 2) expression in both serial dilutions a and b of the sample (Fig. 5a); and 3) expression in both duplicate samples (Fig. 5a, I, II) isolated from different cell-culture passages/RNA preparations.
Here, we investigated the expression of 31 selected genes in a serial measurements design to put special emphasis on the temporal changes of expression during the disease course of LPS-induced acute systemic inflammation.
In summary, we have used a method to analyze gene expression in serial blood samples and identified a set of genes that show differential expression in the blood of patients who develop ISR after BMS implantation, compared to those who do not.
For example, profiling gene expression in a rat model of inflammation using SAGE (serial analysis of gene expression) has provided novel insights into mast cell activation [ 27].
In a serial BrdU labeling assay of cardiac morphogenesis, high-level CENP-F expression was shown to be abruptly downregulated after neonatal day 6.
There was a similarity in localisation between ChREBP and Glut-1 expression in serial sections found in areas of both normal and malignant breast tissue.
Sixty-six oeSCChageal SCC tumours were examined for both EGFR and HER-2 expression in serial sections by IHC.
Lamin expression in serial sections from frozen tissue samples was investigated by single and double indirect immunofluorescence.
