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Accordingly, we stratified the TMA lung SCC cases into PD-L1 protein expression high (proportion of tumor cells expressing PD-L1 > 0.00; n = 147) and protein expression low (proportion of tumor cells expressing PD-L1 = 0.00; n = 260) groups, and formally tested for a statistical interaction between PD-L1 protein expression (high versus low) and the SI score in a CPH survival model.
For this, we used neuroblastoma cells (N2a) that expressed two different levels of PrPC: cells with endogenous expression ("high" expression) and cells in which PrPC expression had been reduced by siRNA targeted at PrPC ("low" expression).
Cases from the TMA cohorts were separated by PD-L1 expression (high versus low).
Watson — with her perpetually startled expression, high, intelligent forehead, and Claymation lips — is not at ease onstage.
Regarding protein, the expression "high protein" is a frequent connotation of an unhealthy diet.
For expression, High Five cells (Expression Systems) at a density of 1 × 106 ml−1 were infected with baculovirus (P1 amplification).
In this context, the GPI-defective DC population shows mannose receptor expression, high levels of the CD86 molecule, and impaired CD1a up-regulation.
To achieve therapeutic CNS transgene expression, high systemic vector doses are often required, which poses challenges such as scale-up costs and dose-dependent hepatotoxicity.
Compared to that of prokaryotes, the expression system of eukaryotes had some other advantages, such as extracellular expression, high purity and posttranslational modification, in the production of heterologous proteins/enzymes (Fernández et al. 2010).
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To identify miRNA regulated by Nanog, we have chosen different cell models in which to modulate the levels of Nanog expression: high-Nanog and low-Nanog expressing cells.
Using KSR1 as a reference standard in a RNAi-based gene expression high-throughput screen termed Functional Signature Ontology (FUSION 7, we identified and validated the γ1 subunit of AMP-activated protein kinase (AMPK) as a contributor to the survival of human colon tumor cells6.
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