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The SMN protein is known to be indispensable within the developing central nervous system, as intracerebroventricular injection of oligos inducing SMN expression have been shown to rescue the phenotype of severely affected SMA mice.
Subsequently, a number of other proteins with roles in post-transcriptional control of gene expression have been shown to colocalize with Exu [36] [42].
Changes in miRNA expression have been shown to occur in cancer [7] However, the nature and impact of most of these changes remain unclear.
Human homolog mutations of many genes with photoreceptor-associated expression have been shown to be associated with retinal diseases including RP [27].
Although changes in ASAP and ACAP expression have been shown to affect cell migration, presumably through effects on actin and adhesion, the molecular mechanism by which they regulate cell migration has yet to be determined.
From another perspective, increases in TGFβ as well as ERK expression have been shown to be involved in JCV multiplication, an effect that can be reversed upon treatment with PD98059 or U0126 [43].
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Ces1d expression has been shown to associate with changes in CLD dynamics.
Cathepsin expression has been shown in some neoplastic tissues and serves as a prognostic indicator.
Elevated PSCA expression has been shown to correlate with malignant phenotype and clinical progression.
This mathematically derived BER expression has been shown to agree with the simulated results, thus validating the derivation.
Transferrin receptor expression has been shown to correlate positively with macrophage infiltration in human carotid atherosclerotic lesions [20].
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