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My lab studies how the genomic sequences that control gene expression function and evolve.
To overcome such challenges, viruses interact with the folding machinery not only as clients but also as regulators of chaperone expression, function, and subcellular localization.
A few of the SNPs identified may have an effect on gene expression, function of the protein and resistance selection processes.
Thus, our results combined with previous published experimental data suggests that inter- and intramolecular disulfide bridges involving C592, C603 and C608 are more important for specific mechanisms as membrane targeting20 or monoclonal antibody binding65, rather than directly affecting the expression, function or activity of the transporter.
(viii) E is an arc expression function.
Ultimately, the integration of several layers of data will be necessary for deconvoluting the relationship between expression, function, and identity.
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Note that the majority of parameters in (17) appear in the argument of the sigmoid regulation-expression function Φ.
A secondary aim was to map the expression of STS during development, with a view to understanding how its altered expression/function might influence ADHD endophenotypes.
Brinkmeier, H. TRP channels in skeletal muscle: gene expression, function and implications for disease.
The importance of this function is expected to be amplified in the context of elevated myofibrillar Ca2+-sensitivity, making even small changes in SERCA2 expression/function highly consequential.
Whether such elements within intron 5 locus convey prostate cancer risk through alteration of FHIT expression/function or through unrelated intronic functional elements remains to be investigated.
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CEO of Professional Science Editing for Scientists @ prosciediting.com