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"You can imagine a scenario where the die is not completely cast… You could possibly mask the gene expression effects of your ancestral experiences," he says.
Fig. 3 Comparison of COX-2 protein expression effects of compounds from V. heyneana.
Conceivably, there may be other effects, including epigenetic, gene regulatory and or expression effects affecting this locus yet to be determined [44].
Few investigations on global gene expression effects of α and β particle irradiation have been performed in normal (thyroid) tissue in vivo.
Fig. 1 COX-2 expression effects of V. heyneana extract (VH) and its fractions (VHH: n-hexane, VHE: ethyl acetate, VHW: water fraction; all 50 µg/mL).
No response was observed with arabinose and ribose, showing that the expression effects were specific for xylose, demonstrating the potential use of the gene circuit as a biosensor.
Concentration-dependent gene expression effects were evaluated in female F344 rat duodenal and jejunal epithelia following 7 and 90 days of exposure to 0.3 520 mg/L (as sodium dichromate dihydrate, SDD) in drinking water.
The present study focuses on early short-term gene expression effects of BDNF.
A high negative connectivity score indicates that the corresponding perturbagen in the CMAP database may reverse the expression effects of the query agent.
Little is known about the significance of these long-range genomic interactions or if they are responsible, mechanistically, for the trans expression effects we describe.
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The Rasgrf1 imprinted cluster in mouse is uniquely positioned as a model to study trans-expression effects for several reasons.
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