Sentence examples for expression did not modify from inspiring English sources

However, reduced levels of MMP-1 or MMP-13 expression did not modify three-dimensional growth of MDA-MB-231 cells, as compared with control cells.

In particular, the exposure of microglial cells to C-CM, despite a modest albeit significant increase in iNOS expression, did not modify iNOS activity, whereas it significantly increased IL-10 and TGFβ gene expression after 24 h.

Acute down regulation of endogenous APP expression did not modify expression levels of APLP1 and APLP2 (Fig 1L), but induced a significant increase in HMGCR mRNA levels (Fig 1M), cholesterol biosynthesis (Fig 1N) and SREBP1 expression (Fig 1O).

However, in another study, the overexpression of human ApoE4 under a murine prion protein promoter (responsible for neuronal and glial expression) did not modify the amount and progression of Aβ deposition in Tg mice expressing human APPswe or APPswe and PS1 with the deletion of exon 9 [ 193].

Accordingly, inhibition of CHC expression does not modify the capacity of HEK293T cells to be infected with CHIKV, supporting that the pathways used to infected this particular cell line is independent of endocytosis by clathrin-coated pits.

In summary, these results duplicate the observation in HEK293 that wild-type or mutant PKD2 expression do not modify the activity of the JAK2/STAT-1/p21/Cdk2 pathway.

First, silencing of Sp1 by siRNA for 24 hours led to inhibition of both TGFβ receptor expression but did not modify Smad3 and Smad7 expression.

Transfection of AP-2α siRNA alone inhibited AP-2α expression but did not modify the AP-2γ transcript level.

Interestingly, although starting treatment with BBG at 40 days significantly affected NOX2 expression, it did not modify disease progression.

Two different shRNA down-regulated the Cdc42 expression, whereas they did not modify the protein expression of Rac1 (Figure 2B, lower panel, see the inset).

By contrast, when used at 0.1 1 μM, rosiglitazone decreased proteoglycan degradation and MMP-1 gene expression, whereas it did not modify chondrocyte nitric oxide production nor COX-2 mRNA expression.