Maximal expression, corrected for differences in cell density, was generally observed between 2 4 hours of induction (Figure 2B; Figure S2B and S2D).
Differential expression (corrected P value (FDR) < 0.1) is detected with the DESeq bioconductor package [ 20] that takes biological and technical variance into account.
Although inhibition of Id2 expression corrected the hyperproliferative phenotype of mutant cells, the contribution of p21/Cdk2 pathway on the abnormal cell proliferation was not clearly addressed [ 17].
Similar results were found for kif21b expression corrected for PMD as with the uncorrected kif21b expression, indicating that it is unlikely that the PMD has influenced the kif21b expression (Additional file 1: Figure S6).
In addition, ΔN-Smg6 and FL-Smg6 expression corrected the accumulation of the PTC+ isoforms which are generated from either exon inclusion or exon exclusion in Smg6∆/∆ ESCs (Supplementary Fig S5D and E).
Psychometric scoring procedures based on emotion expressions corrected for baseline emotion expression, in addition to facial plasticity, might be perceived as fairer approaches in measuring emotion expressive abilities.
Thus, MASS can be thought of as quantifying the absolute change in the downstream gene expressions (corrected for the predicted sign s i of each downstream in the HYP) compared to the total quantity of the downstreams.
Although isolation of human antibodies from the above mentioned systems has been successful, there can be unexpected problems with subsequent therapeutic mAb development due to constraints of protein expression, correct folding and post-translational modifications.
In contrast, when NICD was expressed in sav PFC clones, the polarity phenotypes were rescued as these egg chambers showed significantly higher percentages of correct Stau (53%, n = 72) (Fig. 4B) and Grk/oocyte nucleus (42%, n = 65) localization (Fig. 4D); compare to sav clones without NICD expression: correct Stau localization (3%), correct Grk/oocyte nucleus localization (7%).
Hence, the statistical significance of the estimated beta coefficients and their signs tell us how the corresponding covariates predict sentiment expression after correcting for all other covariate effects.
