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The said score is a combined variation metric, comprised of individual features of MAX/MIN, CV, kurtosis and differential expression consistency.
Prior works show that differential expression consistency is an objective metric providing significant enrichment in the FDA-approved and proposed anti-cancer targets [21].
Even more prominent trend was observed for differential expression consistency (DEXCON) and variability (VAR) that were steadily increasing in proportion to the Index of Multiple participation, being maximal for multiple participants.
To ensure that the extent of variability indeed parallels the objective extent of mechanistic participation, the variability data were aligned with differential expression consistency and metric of tissue-specific expression.
Figure 1 presents normalized levels of expression, consistency of differential expression and integrated panel variability for 54675 probe-sets comprising the high density U133 Plus 2.0 microarray platform by Affymetrix.
Such cases show high expression consistency within the dataset.
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With the RP method, genes in each individual sample are ranked based on the gene-length normalized expression consistencies and differences observed when juxtaposed against the normalized expression of the other samplings by means of a series of pairwise comparisons.
In 1885 Twardowski enrolled at the University of Vienna and became a student of Franz Brentano, for whom he felt "the most sincere awe and veneration" and whom he remembered as "uncompromising and relentless in his quest for rigor in formulation, consistency in expression, and precision in the working out of proofs" (Twardowski 1926 , 20.
However, utilizing gene expression data, consistency scores can only be calculated for interactions involving transcription events, limiting their discriminatory power.
Furthermore, compared with miRNA expression, higher consistency between mRNAs and proteins was observed.
Degree of YKL-40 expression showed consistency with the FNCLCC grading, and survival in patients suffering from ALT/STS.
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expression continuity
articulation consistency
expression coherence
expression evenness
word consistency
expression compatibility
expression uniformity
expression concordance
reflection consistency
expression coherency
expression homogeneity
saying consistency
expression coherent
expression consistent
express consistency
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