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Reproductive isolation is a defining characteristic of populations that represent unique biological species, yet we know very little about the gene expression basis for reproductive isolation.
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Some of the criteria for selection mentioned in Bracquemond and Gaudoin (2003) are simple and flexible expressions, physical basis for the distribution, interpretation of model parameter, and efficiency of estimators.
It is unlikely that regulation of expression is the basis for this difference since available transcription data in the Serial Pattern of Expression Levels Locator (SPELL; spell2.princeton.edu/) database show a high degree of coregulation of homologous pairs of ribosomal genes for cells in exponential and stationary phases as well as during heat shock.
As a first step in evaluating CellSearch® in comparison with the CTC-Chip platforms, all of which use EpCAM expression as the basis for CTC capture, we looked at the utility of EpCAM as a universal marker expressed on cancer cells by evaluating its expression in cell lines and across diverse tumor types.
This, and reports that the ubiquitin-specific protease UBP43 (alternatively USP18) encoded by ISG43 can block type I IFN-induced phosphorylation of Tyr701 on STAT1 and that ISG expression is prolonged in ubp43−/− murine embryonic fibroblast cells [12], led us to examine whether inadequate induction of UBP43 expression is the basis for our observations.
Changes in the normal program of gene expression are the basis for a number of human diseases.
This observation provides strong evidence that BnFLC.A10 underlies variation for vernalization requirement and that differences in gene expression establish the basis for allelic variation at the qFT10-4 locus.
A modified gene expression represents the basis for the development and acquisition of the abnormal growth and differentiation characteristics of tumour cells.
The phage-determined regulation of gene expression provides a basis for understanding and modeling the quantitative dynamics of the intracellular life cycle; this understanding likewise provides a basis for positioning design elements to avoid disrupting genes and regulatory elements.
In contrast to other studies focussing on only gene expression, we evaluated both gene- and exon-level expressions as the basis for a reliable predictor of neuroblastoma outcome.
These simpler expressions provide the basis for the argument that follows, and the bulk viscosity can be left on one side.
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