Sentence examples for expression and the impact from inspiring English sources

We discuss the implications of such regulatory systems regarding the evolution of gene expression and the impact of human genomic structural variations.

Considering that biology, gene regulation and expression, and the impact of a substance on a particular gene can vary so much, it makes perfect sense that animal research is not the best model to determine the long-term health effects of GMOs in humans.

The timing of expression, and the impact of knockdown on excitatory synapse formation, indicates that miR-132 coordinates an instructive transcriptional program that is necessary for the integration of newborn neurons into the adult central nervous system.

Moreover, interactions with the recently described CSNK1A1 expression and the impact on disease outcome were also explored.

Direct comparison of transcriptome and whole genome sequence data for matched individuals allows analysis of allele-specific expression and the impact of variants on expression levels.

Dysregulation of transcription in lupus nephritis is further indicated by the profound effect of alterations in Ets factor/Fli-1 expression and the impact of histone deacetylase inhibitors, which diminish gene transcription, on development and severity of renal disease.

In this study, we explore the role of miR-101 in regulating DNMT3a expression and the impacts of miR-101-DNMT3a miR-101-DNMT3a miR-101-DNMT3aesis.

The current setting of the model is focused on the effects of RASFs on chondrocyte gene expression and excludes the impact of lymphocytes and macrophages.

To examine the autonomy and mechanism of p16INK4a-induced senescence, we utilized a melanoma cell model with inducible, physiological levels of p16INK4a expression and compared the impact of wild-type p16INK4a expression to that of two functionally distinct p16INK4a melanoma-associated mutants.

However, understanding how these findings actually relate to the disease process of schizophrenia requires knowledge both of the factors that might give rise to such changes in gene expression and of the impact of these changes on the function of the affected neural circuits.

We addressed the functional relevance of the TBK1/DDX3X interaction by reducing DDX3X expression and measuring the impact on type-I IFN production.