Sentence examples for expression and the consequences from inspiring English sources

The results, however, are striking and do appear to justify further investigation of the effect of cimetidine on E-selectin expression and the consequences of this interaction on sLA and sLX expressing colonic carcinoma.

Furthermore, we examined the effect of hypoxia on MMP/TIMP expression, and the consequences of changes in the MMP/TIMP balance on migration through collagen by RA synovial fibroblasts.

In view of the recent observation that there is a relationship between decidual PRL expression and reproductive disorders, further research should be directed towards assessing the molecular basis of the reported defects in extrapituitary PRL expression and the consequences of these defects in reproduction.

Fig. 2 summarizes how the methods could be applied to study the effects of SDF-1Î on Tac1 expression, and the consequence to hematopoiesis.

To recapitulate the clinical observation of decreased LKB1 expression and investigate the consequences of decreased LKB1 in ccRCC, shRNA specific to LKB1 was used to knock down the expression of LKB1 in human ccRCC 786-O cells that, among the human ccRCC cell lines, have intermediate LKB1 expression.

For these reasons, we were more interested in pursuing the knockdown of LKB1 in our ccRCC cell lines to recapitulate the clinical observation of decreased LKB1 expression and investigate the consequences of decreased LKB1 in ccRCC.

However, finding the relationship between altered gene or protein expression and the biological consequences is not always straightforward [ 5], especially given that the effect of a single genetic variation is often not limited to one biochemical pathway [ 6].

Beside the remarkable number of reports describing dystrophin gene expression and the pathogenic consequences of the gene mutations in dystrophinopathies, the full scenario of the DMD transcription dynamics remains however, poorly understood.

Alterations to gene expression and the phenotypic consequences of polyploidy are thought to impact the evolutionary potential of polyploids [3], [1].

The mechanism(s) underlying deregulated expression and the clinical consequences of changes in expression are not known.

Joshua Mendell (Johns Hopkins University, MD, USA) described the roles of Myc and p53 in the regulation of miRNA expression and the therapeutic consequences of restoring miR-26a in hepatocellular carcinomas; data produced in his and in Jerry Mendell's laboratories were published in Cell on the same day as the presentation.