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These findings are supported by the expression analyses demonstrating that 5-aza-CdR could activate the expression of CD44 in these cells.
The role of GPNMB in cancer was first discussed based on expression analyses demonstrating that GPNMB expression is particularly high in melanoma and BC cell lines in vitro 14.
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However, genome-wide expression analyses demonstrated that the gene is expressed and that the protein is translated and localizes to both the cytoplasm and the nucleus [32], [33], [34], [35], [36].
Unbiased global gene expression analyses demonstrate that MECP2 functions as a global activator in neurons but not in neural precursors.
Gene expression analyses demonstrated that MP delivery of the GFs resulted in similar expression levels of hepatocytic markers despite the use of 10-fold less total GFs.
Gene expression analyses demonstrated that BBA treatment and overexpression of Nurr1 has a synergistic effect on derivation of DAergic neurons from Nurr1/GPX-1-expressing ES cells.
The results of the sQRT-PCR and reporter expression analyses demonstrate that CovR is required for the increased expression of P1882 under in vivo conditions, while in vitro gel shift and DNase I protection assays show that CovR directly binds to a portion of the intragenic region upstream of SMU.1882.
Further expression analyses demonstrated that the novel genes are region-specific and developmentally regulated.
Our gene expression analyses demonstrated that more than 150 genes are required to obtain major and clearly distinguishable gene clusters.
Expression analyses demonstrated that miR156 was highly abundant in 15-day-old plants but less so in 60-day-old plants.
Taken together, our evolutionary and gene expression analyses demonstrate that our new TFBS predictions significantly improve on the previous annotations and that for a subset of genes, changes in predicted TFBSs correlate significantly with changes in gene expression divergence.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com