Sentence examples for expression alterations of from inspiring English sources

We estimated the similarity of cancer types not only based on all differentially expressed genes, but also based on the expression alterations of cancer-related pathways from KEGG [ 50, 51], including pathways in cancer, cell cycle and the p53 signaling pathway.

Expression alterations of clock genes are associated with key oncogenic pathways, patient survival, tumor stage, and subtype in multiple cancer types.

Active anticancer components are known to exhibit a consistent antitumor effect by blocking abnormal expression alterations of multiple signaling proteins, such as VEGF, p53, JAK-STAT, and CDC14A [454 55] 55].

In contrast, the expression alterations of cell line-specific proteins could more likely have been directly induced by gene dosage modifications.

In this study, we analyzed the expression alterations of a set of miRNAs in neurons and astrocytes subjected to 60 minutes of ischemia and collected at different time-points following this injury.

Therefore expression alterations of p16/Rb signaling were consistent with the model that they are a consequence of changes of cellular PDs and senescence in GR medium suggesting that GR may contribute to increased cellular lifespan via inhibiting the p16/Rb signaling pathway.

In addition, the expression alteration of skeletal muscle-specific cardiac ankyrin repeat protein and the bcl-2 related anti-apoptotic protein Nr-13 suggests possible unique roles for myostatin in regulating myogenesis by controlling cofactors participated transcriptional regulation and apoptosis.

We suspected that the larger amount of accumulation of Na+ in rice shoots induced by the introgression might be related to the expression alteration of genes related to Na+/K+ balance.

Alternatively, parasite nutrient acquisition or expression alteration of some digestive enzymes, as observed for the chymotrypsin-like serine protease discussed below, could inhibit blood digestion and absorption of nutrients leading to decreased number of embryogenesis related genes expression.

However, it is evident that the overall expression alteration of all 25 genes is statistically comparable, although the actual fold change values in real-time PCR and microarray are not always commensurable.

The magnitude of expression alteration of these genes was up to 30-fold.