In viscerosensation this is particularly true for the taste system where, for example, mouse taste bud cells expressing the receptor molecule that is responsive to bitter stimuli have been engineered to express fluorescence, or to be rendered inoperable, and identified as distinct from cells expressing sweet and umami receptors.
In mice, oral vismodegib administration leads to decreased body weight, and reduction in the number of cells expressing sweet taste receptors and downstream signaling molecules.
In the human taste bud, some cells express sweet receptors and respond to sweetness, whereas other cells express bitter receptors and respond to bitter chemicals.
In the present study, the sites where sweet receptors interact with thaumatin were investigated using human embryonic kidney 293 (HEK293) cells expressing the sweet receptors T1R2 T1R3.
In addition to its intestinal expression, GLP-1 was also found to be expressed in taste cells in mouse circumvallate papillae taste buds; it was co-expressed with α-gustducin and T1R3-expressing sweet taste cells in mouse taste buds, and it was produced in taste buds from lingual extracts in its active form [ 79].
Here, we take advantage of the natural variation of sweet and grain sorghum to uncover genes that are conserved in rice, sorghum, and sugarcane but differently expressed in sweet versus grain sorghum by using a microarray platform and the syntenous alignment of rice and sorghum genomic regions containing these genes.
Even Hein's homage to classic, geometry-obsessed minimalism is expressed in sweet, self-effacing terms: thirty-six sugar cubes, perched on an easily overlooked shelf.
A diamond bird motif, with a twist of a tail forming a ring, or a bird flying from a necklace of sky blue chalcedony beads, expressed the sweet side.
Repeating it recently over many hours in Shanghai and New York, Mr. Tian expressed a sweet wonder that it could actually have happened, much less to him, a child of the Cultural Revolution who had seen only one Western opera -- "Carmen," in Chinese -- before coming to the United States nearly 20 years ago.
In this paper, we demonstrated that Lrmp/Jaw1 was selectively expressed in sweet, umami, and bitter taste responsive cells.
In summary, the present study showed that Lrmp/Jaw1 was selectively expressed in sweet, bitter, and umami taste responsive cells.
