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Mice expressing fully edited 5-HT2CR isoforms present with PWS-like symptoms, including hyperphagia and hypotonia [ 44].
Less comprehensive libraries may miss the critical target of the compound of interest and even comprehensive libraries may not have efficient shRNAs against all of the represented genes or all of the cDNAs expressing fully functional proteins.
(B ) Similarly, the working concentration of N1ext-Fc was determined by incubating cells expressing fully induced TO-Jag1-cerulean (orange) and TO-Dll1-cerulean (red) with varying concentrations of N1ext-Fc, and staining with secondary reagents.
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As expected, cells expressing fully-glycosylated ICAM-2 WT formed fewer colonies in soft agar (9.6 ± 1.4) than control transfectants (227 ± 10.1 colonies) (P< 0.0001***, Figure 6).
The in vitro and in vivo phenotypes of cells expressing glycosylation site variants differed from cells expressing fully-glycosylated ICAM-2 or no ICAM-2.
"I will never be able to express fully my profoundly felt gratitude to this great country".
Ms. Giffords nodded, as she often does when Mr. Kelly — as he often does — intuits the many thoughts she is still unable to express fully.
But the prize is big: a global community where dreams and talents can be expressed fully, and where new jobs are made available founded on the Creative Economy.
For Maxwell's equations are expressed fully in terms of these same E and B fields.
It is indeed a "hard problem" when I consider how the brain constructs those many distinct "qualia" – instances of subjective experience which words can never express fully – and builds our conscious experience.
3. Finally, to express fully in a way that is most accessible to all backgrounds and beliefs of an audience.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com