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The genes encoding HLA class I are among the most polymorphic in the human genome [12]: each individual expresses up to six different class I alleles (two at each of the A, B and C loci) out of a pool of over two thousand allelic variants defined to date.
In mammals such as mice and humans, p53 expresses up to 12 protein isoforms generated by alternative splicing, codon initiation sites and internal promoters [ 42, 43].
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A gene was counted as differentially expressed (up- or down-regulated) by expression level of at least one unique probe.
We then detected the pFAK and tFAK expression in the GC transfected cells that expressed up- or downregulated MGr1-Ag/37LRP adhesionhesion to ECM components and control.
We calculated the correlation coefficients between the expression profiles of these TFs and the differentially expressed (up- and down-regulated) genes in saliva in all samples.
moDCs were transduced to express up to three KSHV ORFs (grouped according to their expression profile) and then cultured with autologous CFSE-stained T cells.
But Mrs. Pip got indigestion if she ate in a hurry so she took reservation on the fast express up without stopping and has buffet service.
Proof In the earlier study, we have expressed up- and down-sampling by the factor K in the frequency domain by use of DFT coefficients [11].
For example, genetically engineered plants, such as the genetically engineered maize 'Smartstax' (MON89034 × 1507 × MON88017 × 59122), express up to six Bt toxins, resulting in a much higher concentration of the potentially immunogenic proteins.
Functional annotations for those differentially expressed up- and down-regulated genes were performed through the DAVID 2008 [19].
Not surprisingly, several hundred genes were differentially expressed (up and down) post-siEZH2 transfection.
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